[PLUG-TALK] Fwd: [IP] Study: Reversal of cognitive decline: A novel therapeutic program

glen gepr at ropella.name
Mon Oct 13 23:17:25 UTC 2014


On 10/11/2014 08:54 PM, David Mandel wrote:
> Fasting in an interesting topic in and of itself.  I don't see much in
> the popular medical literature on the value or lack of value of
> fasting.  Indeed, this lack of discussion sort of leads one to conclude
> that modern medicine doesn't put much value on fasting.

I found this paper interesting:

http://www.cell.com/cell-stem-cell/abstract/S1934-5909%2814%2900151-9

> Highlights
>
>     •Prolonged fasting downregulates a IGF-1/PKA pathway in stem cells
>     •Prolong fasting protects hematopoietic cells from chemotoxicity
>     •Prolonged fasting cycles promote HSC self-renewal to reverse immunosuppression
>     •Inhibition of IGF-1 or PKA signaling mimics the effects of prolonged fasting

Longo has published a number of fasting related papers.  I showed this 
paper to my oncologist, however; and she dismissed it out of hand.

-- 
⇒⇐ glen



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